Technology Transfer: Commercialize a Scripps Invention

A rendering of autonomous underwater explorers (AUEs) developed at Scripps.

A rendering of autonomous underwater explorers (AUEs) developed at Scripps.

Through strategic research collaborations with Scripps, corporations and entrepreneurs, nonprofit organizations and investors alike can work with our scientists to translate groundbreaking discoveries into technologies, products, and know-how of intrinsic value and benefit for society and in the marketplace.

Patents, copyrights, trademarks and other forms of intellectual property associated with the innovations of our scientists, students, and staff are assigned to the University of California, San Diego (UCSD) and available for commercial licensing through the UC San Diego Office of Innovation and Commercialization.  A solution to a technical problem or new product for an unmet need may exist among our diverse technology portfolio. 

A license to a Scripps/UCSD invention can cut the cost of R&D by reducing risk and redundant research, accelerate new product development, and complement a company’s existing technologies and capabilities. At a fraction of the cost of initiating a new corporate R&D program or the price of competing commercial options, a firm, entrepreneur or venture investor can secure the rights to tomorrow’s transformative technologies.

Select Technologies Available for Licensing

The following Scripps technologies – including instruments, chemical compounds, and biological materials – are available for licensing and co-development.  For a detailed description, potential uses, intellectual property protection, and other pertinent information, please click on the link to consult the complete abstract provided by the UCSD Office of Innovation and Commercialization (http://invent.ucsd.edu/).  

Marine Natural Products for Drug Discovery (Cancer and Infectious Diseases)
Scripps Oceanography scientists were among the first to explore the natural product chemistry of marine organisms and this research helped to develop the field of marine natural products chemistry and the realization that the oceans harbor myriad new organic molecules with utility for the development of pharmaceuticals and other products. This research led to the discovery of hundreds of new compositions of matter for new products—some of which are already well progressed into commercial development. Two compounds are now entering phase II clinical trials. One of these, Salinosporamide A, is a potent proteasome inhibitor. The second compound, which is derived from the fungal metabolite halimide, acts as a vascular disrupting agent (http://techtransfer.universityofcalifornia.edu/NCD/20990.html).
Therapeutic for Solid Tumors (Colon Cancer)
Scripps Oceanography scientists have mined their rare collection of marine organisms to identify, characterize and analog a proprietary, small molecule with anti-cancer properties. Studies have identified regions of the molecule that have yielded analogs of greatest interest. Compositions of matter and methods of use are claimed for the treatment of cancer and hyper-proliferative disorders (http://techtransfer.universityofcalifornia.edu/NCD/22510.html).
Marine Compounds for Skin Disorders (Acne) and Inflammatory Diseases
Scientists at Scripps Institution of Oceanography have mined their rare collection of marine organisms to identify a family of small molecules (honaucins A-C from the cyanobacteria Leptolyngbya crossbyana) with ideal features for dermatologic indications as well as other inflammatory conditions.  Synthesis of the molecules have revealed essential structural features for activities of interest and provided analogs with greater potency in both anti-inflammatory and quorum sensing inhibitory assays. In addition, the mechanism of action has been partially identified and compounds have shown limited toxicity. Specific indications include acne, psoriasis and other inflammatory dermatologic applications; autoimmune disease, atherosclerosis, and rheumatoid arthritis  (http://techtransfer.universityofcalifornia.edu/NCD/21372.html).
Oil & Gas Exploration: Hydrocarbon Detection
Scripps researchers have invented a new sensor for detecting the presence and measuring the characteristics of hydrocarbon reservoirs. This invention features a design that is more compact and robust than previous designs currently on the market. The invention also allows for specific monitoring of the changes in the reservoir, and not the surrounding geology (http://techtransfer.universityofcalifornia.edu/NCD/20593.html).
 

For a thorough, up-to-date inventory of all disclosed UCSD innovations currently available for licensing, including recent discoveries and inventions by Scripps researchers, we invite you to search the online database maintained by UC San Diego's Office of Innovation and Commercialization: http://invent.ucsd.edu/.

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