| Title | 4Z- and 4E-12-deoxydihydrokromycins, two naturally occurring kromycin aglycones of pikromycin from Streptomyces sp |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Yang I., Yoon J., Kim D., Hahn D., Nam SJ, Fenical W |
| Journal | Tetrahedron Letters |
| Volume | 58 |
| Pagination | 2322-2324 |
| Date Published | 2017/06 |
| Type of Article | Article |
| ISBN Number | 0040-4039 |
| Accession Number | WOS:000403528100003 |
| Keywords | 14-Membered macrolide; derivatives; Kromycin derivative; Marine-derived Streptomyces; narbomycin; Pikromycin aglycone; sp.; venezuelae; yc-17 |
| Abstract | HPLC-UV guided isolation for the culture broth extract of the marine-derived bacterium Streptomyces sp. has led to the two 14-membered macrolides, 4Z- (1) and 4E-12-dehydroxykromycins (2). The chemical structures of compounds 1 and 2 were elucidated by spectral data, while the absolute stereochemistry of 1 and 2 were determined by application of circular dichroism (CD) and analysis of X-ray crystallographic data. (C) 2017 Published by Elsevier Ltd. |
| DOI | 10.1016/j.tetlet.2017.03.088 |
| Short Title | Tetrahedron Lett. |
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