Molluscan models: Crepidula fornicata

TitleMolluscan models: Crepidula fornicata
Publication TypeJournal Article
Year of Publication2016
AuthorsHenry J.Q, Lyons D.C
JournalCurrent Opinion in Genetics & Development
Volume39
Pagination138-148
Date Published2016/08
Type of ArticleArticle
ISBN Number0959-437X
Accession NumberWOS:000388922900020
Keywordscalyptraeid gastropods; crassostrea-gigas; embryo; european mussels; gastropod crepidula; gene regulatory network; introduced suspension-feeders; invasive mollusk; sea-urchin; slipper limpet; spiralian gastrulation
Abstract

Gastropod snails in the genus Crepidula have emerged as model systems for studying a metazoan super clade, the Spiralia. Recent work on one species in particular, Crepidula fornicata, has produced high-resolution cell lineage fate maps, details of morphogenetic events during gastrulation, key insights into the molecular underpinnings of early development, and the first demonstration of CRISPR/Cas9 genome editing in the Spiralia. Furthermore, invasive species of Crepidula are a significant ecological threat, while one of these, C. fornicata, is also being harvested for food. This review highlights progress towards developing these animals as models for evolutionary, developmental, and ecological studies. Such studies have contributed greatly to our understanding of biology in a major clade of bilaterians. This information may also help us to control and cultivate these snails.

DOI10.1016/j.gde.2016.05.021
Short TitleCurr. Opin. Genet. Dev.
Student Publication: 
No