Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens

TitleParguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens
Publication TypeJournal Article
Year of Publication2013
AuthorsMeyers E., Byrum T., Gerwick WH
JournalJournal of Natural Products
Volume76
Pagination1810-1814
Date Published2013/09
Type of ArticleArticle
ISBN Number0163-3864
Accession NumberWOS:000330331200039
Keywordslyngbya-majuscula
Abstract

Two new marine cyanobacterial natural products, parguerene (1) and precarriebowmide (2), were isolated from a collection of Moorea producens obtained from La Parguera, Puerto Rico. The planar structures of both were deduced by 2D NMR spectroscopy and mass spectrometry. Parguerene is a modified acyl amide with some structural similarity to the bacterial metabolite stipiamide (3), whereas precarriebowmide is a lipopeptide and represents a minor modification compared to two other known metabolites, carriebowmide (4) and carriebowmide sulfone (5). The identification of 2 led to an investigation into whether carriebowmide and carriebowmide sulfone were true secondary metabolites or isolation artifacts.

DOI10.1021/np400347f
Short TitleJ. Nat. Prod.
Integrated Research Themes: 
Student Publication: 
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