The "Residential" Effect Fallacy in Neighborhood and Health Studies Formal Definition, Empirical Identification, and Correction

TitleThe "Residential" Effect Fallacy in Neighborhood and Health Studies Formal Definition, Empirical Identification, and Correction
Publication TypeJournal Article
Year of Publication2017
AuthorsChaix B., Duncan D., Vallee J., Vernez-Moudon A., Benmarhnia T., Kestens Y.
JournalEpidemiology
Volume28
Pagination789-797
Date Published2017/11
Type of ArticleArticle
ISBN Number1044-3983
Accession NumberWOS:000411901200014
Keywordsactivity spaces; associations; built environment; exposure; modes; physical-activity; record cohort; research agenda; risk-factors; self-rated health; transportation
Abstract

Background: Because of confounding from the urban/rural and socioeconomic organizations of territories and resulting correlation between residential and nonresidential exposures, classically estimated residential neighborhood-outcome associations capture nonresidential environment effects, overestimating residential intervention effects. Our study diagnosed and corrected this "residential" effect fallacy bias applicable to a large fraction of neighborhood and health studies. Methods: Our empirical application investigated the effect that hypothetical interventions raising the residential number of services would have on the probability that a trip is walked. Using global positioning systems tracking and mobility surveys over 7 days (227 participants and 7440 trips), we employed a multilevel linear probability model to estimate the trip-level association between residential number of services and walking to derive a naive intervention effect estimate and a corrected model accounting for numbers of services at the residence, trip origin, and trip destination to determine a corrected intervention effect estimate (true effect conditional on assumptions). Results: There was a strong correlation in service densities between the residential neighborhood and nonresidential places. From the naive model, hypothetical interventions raising the residential number of services to 200, 500, and 1000 were associated with an increase by 0.020, 0.055, and 0.109 of the probability of walking in the intervention groups. Corrected estimates were of 0.007, 0.019, and 0.039. Thus, naive estimates were overestimated by multiplicative factors of 3.0, 2.9, and 2.8. Conclusions: Commonly estimated residential intervention-outcome associations substantially overestimate true effects. Our somewhat paradoxical conclusion is that to estimate residential effects, investigators critically need information on nonresidential places visited.

DOI10.1097/ede.0000000000000726
Short TitleEpidemiology
Student Publication: 
No