Found 28 results
Filters: Keyword is discovery  [Clear All Filters]
Tuttle R.N, Demko A.M, Patin NV, Kapono C.A, Donia M.S, Dorrestein P., Jensen PR.  2019.  Detection of natural products and their producers in ocean sediments. Applied and Environmental Microbiology. 85
Dhaneesha M., Hasin O., Sivakumar K.C, Ravinesh R., Naman C.B, Carmeli S., Sajeevan T.P.  2019.  DNA binding and molecular dynamic studies of polycyclic tetramate macrolactams (PTM) with potential anticancer activity isolated from a sponge-associated Streptomyces zhaozhouensis subsp. mycale subsp. nov. Marine Biotechnology. 21:124-137.
Roux S., Adriaenssens E.M, Dutilh B.E, Koonin E.V, Kropinski A.M, Krupovic M., Kuhn J.H, Lavigne R., Brister J.R, Varsani A. et al..  2019.  Minimum information about an uncultivated virus genome (MIUViG). Nature Biotechnology. 37:29-37.
Kearney S.E, Zahoranszky-Kohalmi G., Brimacombe K.R, Henderson M.J, Lynch C., Zhao T.G, Wan K.K, Itkin Z., Dillon C., Shen M. et al..  2018.  Canvass: A crowd-sourced, natural-product screening library for exploring biological space. 4:1727-1741.
Bruns H., Crusemann M., Letzel A.C, Alanjary M., McInerney J.O, Jensen PR, Schulz S., Moore BS, Ziemert N..  2018.  Function-related replacement of bacterial siderophore pathways. Isme Journal. 12:320-329.
Moss N.A, Leao T., Rankin M.R, McCullough T.M, Qu P.P, Korobeynikov A., Smith J.L, Gerwick L, Gerwick WH.  2018.  Ketoreductase domain dysfunction expands chemodiversity: Malyngamide biosynthesis in the cyanobacterium Okeania hirsuta. Acs Chemical Biology. 13:3385-3395.
LaMonte G.M, Almaliti J., Bibo-Verdugo B., Keller L., Zou B.Y, Yang J., Antonova-Koch Y., Orjuela-Sanchez P., Boyle C.A, Vigil E. et al..  2017.  Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. Journal of Medicinal Chemistry. 60:6721-6732.
Letzel A.C, Li J., Amos G.CA, Millan-Aguinaga N., Ginigini J., Abdelmohsen U.R, Gaudencio S.P, Ziemert N., Moore BS, Jensen PR.  2017.  Genomic insights into specialized metabolism in the marine actinomycete Salinispora. Environmental Microbiology. 19:3660-3673.
Asolkar R.N, Singh A., Jensen PR, Aalbersberg W., Carte B.K, Feussner K.D, Subramani R., DiPasquale A., Rheingold A.L, Fenical W.  2017.  Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete Glade MAR4. Tetrahedron. 73:2234-2241.
Crusemann M., O'Neill E.C, Larson C.B, Melnik A.V, Floros D.J, da Silva R.R, Jensen PR, Dorrestein PC, Moore BS.  2017.  Prioritizing natural product diversity in a collection of 146 bacterial strains based on growth and extraction protocols. Journal of Natural Products. 80:588-597.
Kersten RD, Lee S., Fujita D., Pluskal T., Kram S., Smith JE, Iwai T., Noel J.P, Fujita M., Weng J.K.  2017.  A Red Algal Bourbonane Sesquiterpene Synthase Defined by Microgram-Scale NMR-Coupled Crystalline Sponge X-ray Diffraction Analysis. Journal of the American Chemical Society. 139:16838-16844.
Paerl R.W, Bouget F.Y, Lozano J.C, Verge V., Schatt P., Allen EE, Palenik B, Azam F.  2017.  Use of plankton-derived vitamin B1 precursors, especially thiazole-related precursor, by key marine picoeukaryotic phytoplankton. Isme Journal. 11:753-765.
Hassan H.M, Boonlarppradab C., Fenical W.  2016.  Actinoquinolines A and B, anti-inflammatory quinoline alkaloids from a marine-derived Streptomyces sp., strain CNP975. Journal of Antibiotics. 69:511-514.
Le T.C, Yang I., Yoon Y.J, Nam SJ, Fenical W.  2016.  Ansalactams B-D illustrate further biosynthetic plasticity within the ansamycin pathway. Organic Letters. 18:2256-2259.
Jordan P.A, Moore BS.  2016.  Biosynthetic pathway connects cryptic ribosomally synthesized posttranslationally modified peptide genes with pyrroloquinoline alkaloids. Cell Chemical Biology. 23:1504-1514.
Lee J., Han C., Lee T.G, Chin J., Choi H., Lee W., Paik M.J, Won D.H, Jeong G., Ko J. et al..  2016.  Marinopyrones A-D, alpha-pyrones from marine-derived actinomycetes of the family Nocardiopsaceae. Tetrahedron Letters. 57:1997-2000.
Floros D.J, Jensen PR, Dorrestein PC, Koyama N..  2016.  A metabolomics guided exploration of marine natural product chemical space. Metabolomics. 12
Wang M.X, Carver J.J, Phelan VV, Sanchez LM, Garg N., Peng Y., Nguyen D.D, Watrous J., Kapono C.A, Luzzatto-Knaan T. et al..  2016.  Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34:828-837.
Bonet B., Teufel R., Crusemann M., Ziemert N., Moore BS.  2015.  Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin. Journal of Natural Products. 78:539-542.
Hassan H.M, Degen D., Jang K.H, Ebright R.H, Fenical W.  2015.  Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine- derived Streptomyces sp. Journal of Antibiotics. 68:206-209.
Ross AC, Gulland L.ES, Dorrestein PC, Moore BS.  2015.  Targeted capture and heterologous expression of the pseudoalteromonas alterochromide gene cluster in Escherichia coil represents a promising natural product exploratory platform. ACS Synthetic Biology. 4:414-420.
Paerl R.W, Bertrand E.M, Allen A.E, Palenik B, Azam F.  2015.  Vitamin B1 ecophysiology of marine picoeukaryotic algae: Strain-specific differences and a new role for bacteria in vitamin cycling. Limnology and Oceanography. 60:215-228.
Mohimani H., Kersten RD, Liu W.T, Wang M.X, Purvine S.O, Wu S., Brewer H.M, Pasa-Tolic L., Bandeira N., Moore BS et al..  2014.  Automated genome mining of ribosomal peptide natural products. Acs Chemical Biology. 9:1545-1551.
Farnaes L., La Clair J.J, Fenical W.  2014.  Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94. Organic & Biomolecular Chemistry. 12:418-423.
Tan L.T, Okino T., Gerwick WH.  2013.  Bouillonamide: A mixed polyketide-peptide cytotoxin from the marine cyanobacterium Moorea bouillonii. Marine Drugs. 11:3015-3024.