Biblio

Found 24 results
Filters: Keyword is drug discovery  [Clear All Filters]
2019
Hammons J.C, Trzoss L., Jimenez P.C, Hirata A.S, Costa-Lotufo L.V, La Clair J.J, Fenical W.  2019.  Advance of seriniquinone analogues as melanoma agents. 10:186-190.
Choi H., Engene N, Byrum T., Hwang S., Oh D.C, Gerwick WH.  2019.  Dragocins A-D, structurally intriguing cytotoxic metabolites from a Panamanian marine cyanobacterium. Organic Letters. 21:266-270.
Hou X.M, Wang C.Y, Gerwick WH, Shao C.L.  2019.  Marine natural products as potential anti-tubercular agents. 165:273-292.
2018
O'Rourke A., Kremb S., Duggan BM, Sioud S., Kharbatia N., Raji M., Emwas A.H, Gerwick WH, Voolstra C.R.  2018.  Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. Molecules. 23
Mascuch S.J, Boudreau P.D, Carland T.M, Pierce N.T, Olson J., Hensler M.E, Choi H., Campanale J., Hamdoun A., Nizet V. et al..  2018.  Marine natural product honaucin A attenuates inflammation by activating the Nrf2-ARE pathway. Journal of Natural Products. 81:506-514.
Patin NV, Floros D.J, Hughes CC, Dorrestein PC, Jensen PR.  2018.  The role of inter-species interactions in Salinispora specialized metabolism. Microbiology-Sgm. 164:946-955.
2017
Luzzatto-Knaan T., Garg N., Wang M.X, Glukhov E., Peng Y., Ackermann G., Amir A., Duggan BM, Ryazanov S., Gerwick L et al..  2017.  Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. Elife. 6
Almaliti J., Malloy K.L, Glukhov E., Spadafora C., Gutierrez M., Gerwick WH.  2017.  Dudawalamides A-D, antiparasitic cyclic depsipeptides from the marine cyanobacterium Moorea producens. Journal of Natural Products. 80:1827-1836.
Machado H., Tuttle R.N, Jensen PR.  2017.  Omics-based natural product discovery and the lexicon of genome mining. Current Opinion in Microbiology. 39:136-142.
Lee H.W, Choi H., Nam SJ, Fenical W, Kim H.  2017.  Potent Inhibition of Monoamine Oxidase B by a Piloquinone from Marine-Derived Streptomyces sp CNQ-027. Journal of Microbiology and Biotechnology. 27:785-790.
2016
O'Rourke A., Kremb S., Bader T.M, Helfer M., Schmitt-Kopplin P., Gerwick WH, Brack-Werner R., Voolstra C.R.  2016.  Alkaloids from the sponge Stylissa carteri present prospective scaffolds for the inhibition of Human Immunodeficiency Virus 1 (HIV-1). Marine Drugs. 14
Videau P., Wells K.N, Singh A.J, Gerwick WH, Philmus B..  2016.  Assessment of Anabaena sp strain PCC 7120 as a heterologous expression host for cyanobacterial natural products: production of lyngbyatoxin A. ACS Synthetic Biology. 5:978-988.
La Clair J.J, Fenical W, Costa-Lotufo L.V.  2016.  Elucidating the mode of action of marine natural products through an immunoaffinity fluorescent (iaf) approach. Journal of the Brazilian Chemical Society. 27:1346-1354.
Bertin M.J, Demirkiran O., Navarro G., Moss N.A, Lee J., Goldgof G.M, Vigil E., Winzeler E.A, Valeriote F.A, Gerwick WH.  2016.  Kalkipyrone B, a marine cyanobacterial gamma-pyrone possessing cytotoxic and anti-fungal activities. Phytochemistry. 122:113-118.
Schorn M.A, Alanjary M.M, Aguinaldo K., Korobeynikov A., Podell S, Patin N., Lincecum T., Jensen PR, Ziemert N., Moore BS.  2016.  Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters. Microbiology-Sgm. 162:2075-2086.
2015
Brito A., Gaifem J., Ramos V, Glukhov E., Dorrestein PC, Gerwick WH, Vasconcelos VM, Mendes M.V, Tamagnini P..  2015.  Bioprospecting Portuguese Atlantic coast cyanobacteria for bioactive secondary metabolites reveals untapped chemodiversity. Algal Research-Biomass Biofuels and Bioproducts. 9:218-226.
Alvarez-Mico X, Rocha D.D, Guimaraes L.A, Ambrose A., Chapman E., Costa-Lotufo L.V, La Clair J.J, Fenical W.  2015.  The hybrid pyrroloisoindolone-dehydropyrrolizine alkaloid (-)-chlorizidine a targets proteins within the glycolytic pathway. Chembiochem. 16:2002-2006.
2014
Jensen PR, Chavarria K.L, Fenical W, Moore BS, Ziemert N..  2014.  Challenges and triumphs to genomics-based natural product discovery. Journal of Industrial Microbiology & Biotechnology. 41:203-209.
Yamanaka K, Reynolds K.A, Kersten RD, Ryan K.S, Gonzalez D.J, Nizet V., Dorrestein PC, Moore BS.  2014.  Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proceedings of the National Academy of Sciences of the United States of America. 111:1957-1962.
Ziemert N., Lechner A., Wietz M., Millan-Aguinaga N., Chavarria K.L, Jensen PR.  2014.  Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora. Proceedings of the National Academy of Sciences of the United States of America. 111:E1130-E1139.
Mevers E., Matainaho T., Allara M., Di Marzo V., Gerwick WH.  2014.  Mooreamide A: A cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii. Lipids. 49:1127-1132.
Trzoss L., Fukuda T, Costa-Lotufo L.V, Jimenez P., La Clair J.J, Fenical W.  2014.  Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin. Proceedings of the National Academy of Sciences of the United States of America. 111:14687-14692.
2013
Engene N, Paul VJ, Byrum T., Gerwick WH, Thor A., Ellisman M.H.  2013.  Chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. Nov (oscillatoriales, cyanoprokaryota). Journal of Phycology. 49:1095-1106.
Kersten RD, Ziemert N., Gonzalez D.J, Duggan BM, Nizet V., Dorrestein PC, Moore BS.  2013.  Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proceedings of the National Academy of Sciences of the United States of America. 110:E4407-E4416.