Found 74 results
Filters: Author is Gerwick, W. H.  [Clear All Filters]
Mehrotra S., Duggan BM, Tello-Aburto R., Newar T.D, Gerwick WH, Murray T.F, Maio W.A.  2014.  Detailed Analysis of (-)-Palmyrolide A and Some Synthetic Derivatives as Voltage-Gated Sodium Channel Antagonists. Journal of Natural Products. 77:2553-2560.
Vogel C.V, Pietraszkiewicz H., Sabry O.M, Gerwick WH, Valeriote F.A, Vanderwal C.D.  2014.  Enantioselective divergent syntheses of several polyhalogenated plocamium monoterpenes and evaluation of their selectivity for solid tumors. Angewandte Chemie-International Edition. 53:12205-12209.
Trivella D.BB, Pereira A.R, Stein M.L, Kasai Y., Byrum T., Valeriote F.A, Tantillo D.J, Groll M., Gerwick WH, Moore BS.  2014.  Enzyme inhibition by hydroamination: Design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chemistry & Biology. 21:782-791.
Meyers E., Haeckl F.PJ, Boudreau P.D, Byrum T., Dorrestein PC, Valeriote F.A, Gerwick WH.  2014.  Lipopeptides from the tropical marine cyanobacterium Symploca sp. Journal of Natural Products. 77:969-975.
Miller B., Friedman A.J, Choi H., Hogan J., McCammon J.A, Hook V., Gerwick WH.  2014.  The marine cyanobacterial metabolite gallinamide a is a potent and selective inhibitor of human cathepsin l. Journal of Natural Products. 77:92-99.
Moree WJ, McConnell O.J, Nguyen D.D, Sanchez LM, Yang Y.L, Zhao X.L, Liu W.T, Boudreau P.D, Srinivasan J., Atencio L. et al..  2014.  Microbiota of healthy corals are active against fungi in a light-dependent manner. Acs Chemical Biology. 9:2300-2308.
Mevers E., Matainaho T., Allara M., Di Marzo V., Gerwick WH.  2014.  Mooreamide A: A cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii. Lipids. 49:1127-1132.
Gong J., Sun P., Jiang N., Riccio R., Lauro G., Bifulco G., Li T.J, Gerwick WH, Zhang W..  2014.  New steroids with a rearranged skeleton as (h)P300 inhibitors from the sponge Theonella swinhoei. Organic Letters. 16:2224-2227.
Xu D.X, Sun P., Kurtan T., Mandi A., Tang H., Liu B.S, Gerwick WH, Wang Z.W, Zhang W..  2014.  Polyhydroxy cyclohexanols from a Dendrodochium sp fungus associated with the sea cucumber Holothuria nobilis Selenka. Journal of Natural Products. 77:1179-1184.
Winnikoff J.R, Glukhov E., Watrous J., Dorrestein PC, Gerwick WH.  2014.  Quantitative molecular networking to profile marine cyanobacterial metabolomes. Journal of Antibiotics. 67:105-112.
Leao PN, Costa M, Ramos V, Pereira A.R, Fernandes V.C, Domingues V.F, Gerwick WH, Vasconcelos VM, Martins R..  2013.  Antitumor activity of hierridin b, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains. Plos One. 8
Tan L.T, Okino T., Gerwick WH.  2013.  Bouillonamide: A mixed polyketide-peptide cytotoxin from the marine cyanobacterium Moorea bouillonii. Marine Drugs. 11:3015-3024.
Engene N, Paul VJ, Byrum T., Gerwick WH, Thor A., Ellisman M.H.  2013.  Chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. Nov (oscillatoriales, cyanoprokaryota). Journal of Phycology. 49:1095-1106.
Leao PN, Ramos V, Goncalves PB, Viana F, Lage OM, Gerwick WH, Vasconcelos VM.  2013.  Chemoecological Screening Reveals High Bioactivity in Diverse Culturable Portuguese Marine Cyanobacteria. Marine Drugs. 11:1316-1335.
Whicher J.R, Smaga S.S, Hansen D.A, Brown W.C, Gerwick WH, Sherman D.H, Smith J.L.  2013.  Cyanobacterial polyketide synthase docking domains: A tool for engineering natural product biosynthesis. Chemistry & Biology. 20:1340-1351.
Gerwick WH, Fenner AM.  2013.  Drug Discovery from Marine Microbes. Microbial Ecology. 65:800-806.
Ongley S.E, Bian X.Y, Zhang Y.M, Chau R., Gerwick WH, Muller R, Neilan B.A.  2013.  High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium. Acs Chemical Biology. 8:1888-1893.
Gerwick L, Boudreau P., Choi H., Mascuch S., Villa F.A, Balunas M.J, Malloy K.L, Teasdale M.E, Rowley DC, Gerwick WH.  2013.  Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites. Phytochemistry Reviews. 12:459-465.
Trentacoste E.M, Shrestha RP, Smith S.R, Gle C., Hartmann A.C, Hildebrand M, Gerwick WH.  2013.  Metabolic engineering of lipid catabolism increases microalgal lipid accumulation without compromising growth. Proceedings of the National Academy of Sciences of the United States of America. 110:19748-19753.
Yang J.Y, Sanchez LM, Rath C.M, Liu X.T, Boudreau P.D, Bruns N., Glukhov E., Wodtke A., de Felicio R., Fenner A. et al..  2013.  Molecular networking as a dereplication strategy. Journal of Natural Products. 76:1686-1699.
Ortega HE, Graupner PR, Asai Y, TenDyke K, Qiu DY, Shen YYC, Rios N, Arnold AE, Coley PD, Kursar TA et al..  2013.  Mycoleptodiscins A and B, Cytotoxic Alkaloids from the Endophytic Fungus Mycoleptodiscus sp F0194. Journal of Natural Products. 76:741-744.
Meyers E., Byrum T., Gerwick WH.  2013.  Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens. Journal of Natural Products. 76:1810-1814.
Engene N, Gunasekera SP, Gerwick WH, Paul VJ.  2013.  Phylogenetic Inferences Reveal a Large Extent of Novel Biodiversity in Chemically Rich Tropical Marine Cyanobacteria. Applied and Environmental Microbiology. 79:1882-1888.
Pavlik C.M, Wong C.YB, Ononye S., Lopez D.D, Engene N, McPhail K.L, Gerwick WH, Balunas M.J.  2013.  Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. Journal of Natural Products. 76:2026-2033.