SCRIPPS INSTITUTION OF OCEANOGRAPHY FACULTY CANDIDATE SEMINAR -
Marine Natural Products and Chemical Biology (joint hire with SSPPS)
DATE: January 23rd, Thursday, 11:15 a.m.
LOCATION: Eckart 227 (a chalk talk will be held 1/24 at noon in the Pharmaceutical Science Building HSEC #2)
SPEAKER: Monica McCallum
TITLE: Synthetic and Microbial Approaches to Natural Products
Small molecules produced by the secondary metabolism of living organisms have long fascinated scientists with their structural complexity and biological activity. These natural products have inspired generations of synthetic chemists and biochemists, both to reconstruct them in the laboratory and to elucidate their means of production in nature. This seminar will examine natural products from both of these perspectives: the total synthesis of hippolachnin A, a cyclobutane containing polyketide, and the biosynthesis of alanosine, with a focus on its unusual nitrogen-nitrogen bond.