EMBARGOED BY PROCEEDINGS OF THE ROYAL SOCIETY B
FOR RELEASE ON Tuesday, April 30, 2013 04:01 PM PDT
Scripps Institution of Oceanography / University of California, San Diego
Only within the past 12 years have marine biologists come to learn about the eye-opening characteristics of mystifying sea worms that live and thrive on the bones of whale carcasses.
A female Osedax with an exposed 'root' system, which secretes acid to penetrate into the bone. Credit: Greg Rouse
With each new study, scientists have developed a better grasp on the biology of Osedax, a genus of mouthless and gutless "bone worms" that make a living on skeletons lying on the seafloor. In the latest finding, scientists at Scripps Institution of Oceanography at UC San Diego describe how the wispy worms are able to carry out their bone-drilling activities. As published in the May 1 online edition of the Proceedings of the Royal Society B (Biological Sciences), Martín Tresguerres, Sigrid Katz, and Greg Rouse of Scripps detail how Osedax excrete a bone-melting acid to gain entry to the nutrients within whale bones.
"The acid presumably allows the worms to release and absorb collagen and lipids that are trapped in bone," said Tresguerres. "This model is remarkably similar to how mammals repair and remodel bone, however Osedax secrete acid to dissolve foreign bone and access nutrients."
In their report, the scientists describe a process in which the worms use a "proton pump" to secrete acid onto the bone. Tresguerres says similar acid-secreting enzymes exist in all other organisms, such as in human kidneys to handle blood and urine functions.
Top: External view of an Osedax specimen. Bottom: Fluorescent labeling of acid-secreting enzyme (green) and cell nuclei (blue). Credit: Greg Rouse, Martin Tresguerres, Sigrid Katz
Because they lack mouths, bone worms must use an alternative method of consuming nutrients from whale bones. Bacteria that live symbiotically within the worms are involved in this process, however, the exact mechanism is not yet fully understood. Some evidence suggests that the symbiotic bacteria metabolize bone-derived collagen into other diverse organic compounds, and that the worms subsequently digest the bacteria for their own nutrition.
"The Osedax symbiosis shows that nutrition is even more diverse than we imagined and our results are one step closer in untangling the special relationship between the worm and its bacteria," said Katz, a Scripps postdoctoral researcher.
A 2011 study led by Rouse found that bone worms have primarily been found attached to whale skeletons, but they are capable of making a living on other bones as well, including fish (http://scrippsnews.ucsd.edu/Releases/?releaseID=1153). That finding supported a hypothesis that Osedax's bone-eating lifestyle may have evolved millions of years ago, even before the dawn of marine mammals.
To continue learning more about bone worms, the scientists plan to collaborate with colleagues at the Monterey Bay Aquarium Research Institute in the coming months to collect and study additional bone samples with live worm specimens. They also plan to maintain live Osedax in aquaria at Scripps to study their physiology.
"Determining how Osedax gets into bones was the first challenge in understanding the nutrition of these bizarre animals," said Rouse. "Now we'd like to understand how they transport and utilize the nutrients that they have uncovered."
Scripps Institution of Oceanography and an Erwin Schrodinger postdoctoral fellowship (Austrian Science Fund) supported the research.
Scripps Institution of Oceanography at the University of California San Diego, is one of the oldest, largest, and most important centers for global science research and education in the world. Now in its second century of discovery, the scientific scope of the institution has grown to include biological, physical, chemical, geological, geophysical, and atmospheric studies of the earth as a system. Hundreds of research programs covering a wide range of scientific areas are under way today on every continent and in every ocean. The institution has a staff of more than 1,400 and annual expenditures of approximately $195 million from federal, state, and private sources. Scripps operates oceanographic research vessels recognized worldwide for their outstanding capabilities. Equipped with innovative instruments for ocean exploration, these ships constitute mobile laboratories and observatories that serve students and researchers from institutions throughout the world. Birch Aquarium at Scripps serves as the interpretive center of the institution and showcases Scripps research and a diverse array of marine life through exhibits and programming for more than 430,000 visitors each year. Learn more at scripps.ucsd.edu and follow us at Facebook, Twitter, and Instagram.
About UC San Diego
At the University of California San Diego, we constantly push boundaries and challenge expectations. Established in 1960, UC San Diego has been shaped by exceptional scholars who aren’t afraid to take risks and redefine conventional wisdom. Today, as one of the top 15 research universities in the world, we are driving innovation and change to advance society, propel economic growth, and make our world a better place. Learn more at www.ucsd.edu.