Scripps Institution of Oceanography at UC San Diego presents the Richard H. and Glenda G. Rosenblatt Lecture in Evolutionary Biology series. Join us as Scott V. Edwards, Professor in the Department of OEB and Curator in the Museum of Comparative Zoology at Harvard University, presents the following lecture:
‘PhyloG2P’ is a monicer for the paradigm in evolutionary genmics of linking genomic variation to phenotypes using phylogenetic trees. PhyloG2P methods capitalize on different genomic signatures – presence/absence of genes, loss of function of genes, insertions and deletions, and shifting evolutionary rates – to find the genomic drivers of phenotypic change on clades that are not amenable to classical genetic approaches. In this talk I will present details of the PhyloAcc (‘Phylo-A-see-see’) family of Bayesian approaches to PhyloG2P and their application to diverse phenotypic traits in birds and mammals.